McDonnell, Donald: search on Z-Library

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1

Identification and Structure−Activity Relationship of Phenolic Acyl Hydrazones as Selective Agonists for the Estrogen-Related Orphan Nuclear Receptors ERRβ and ERRγ

Zuercher, William J., Gaillard, Stéphanie, Orband-Miller, Lisa A., Chao, Esther Y. H., Shearer, Barry G., Jones, David G., Miller, Aaron B., Collins, Jon L., McDonnell, Donald P., Willson, Timothy M.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

2

Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer

Allensworth, Jennifer L., Evans, Myron K., Bertucci, François, Aldrich, Amy J., Festa, Richard A., Finetti, Pascal, Ueno, Naoto T., Safi, Rachid, McDonnell, Donald P., Thiele, Dennis J., Van Laere, St

Journal:

Molecular Oncology

Year:

2015

Language:

english

File:

PDF, 3.76 MB

english, 2015

3

Decoding the Inversion Symmetry Underlying Transcription Factor DNA-Binding Specificity and Functionality in the Genome

Coons, Laurel A., Burkholder, Adam B., Hewitt, Sylvia C., McDonnell, Donald P., Korach, Kenneth S.

Journal:

Year:

2019

Language:

english

File:

PDF, 41.60 MB

english, 2019

4

The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: Implications for the treatment and prevention of osteoporosis

Nelson, Erik R., Wardell, Suzanne E., McDonnell, Donald P.

Journal:

Year:

2013

Language:

english

File:

PDF, 700 KB

english, 2013

5

Development of peptide antagonists that target estrogen receptor–cofactor interactions

Donald P. McDonnell, Ching-Yi Chang, John D. Norris

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2000

Language:

english

File:

PDF, 375 KB

english, 2000

6

Cellular Mechanisms Which Distinguish between Hormone- and Antihormone-Activated Estrogen Receptor

Donald P. McDonnell, Sharon L. Dana, PATRICIA A. HOENER, BENJAMIN A. LIEBERMAN, MARKUS O. IMHOF, ROBERT B. STEIN

Journal:

Annals of the New York Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 956 KB

english, 1995

7

10.1071/RD00108

Safe, Stephen H., Pallaroni, Lea, Yoon, Kyungsil, Gaido, Kevin, Ross, Susan, Saville, Brad, McDonnell, Donald

Journal:

Reproduction Fertility and Development

Year:

2001

Language:

english

File:

PDF, 140 KB

english, 2001

8

Distinct receptor tyrosine kinase subsets mediate anti-HER2 drug resistance in breast cancer

Alexander, Peter B., Chen, Rui, Gong, Chang, Yuan, Lifeng, Jasper, Jeff S., Ding, Yi, Markowitz, Geoffrey J., Yang, Pengyuan, Xu, Xin, McDonnell, Donald P., Song, Erwei, Wang, Xiao-Fan

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.86 MB

english, 2016

9

The Endogenous Selective Estrogen Receptor Modulator 27-Hydroxycholesterol Is a Negative Regulator of Bone Homeostasis

DuSell, Carolyn D., Nelson, Erik R., Wang, Xiaojuan, Abdo, Jennifer, Mödder, Ulrike I., Umetani, Michihisa, Gesty-Palmer, Diane, Javitt, Norman B., Khosla, Sundeep, McDonnell, Donald P.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 33 KB

english, 2010

10

Problems for Risk Assessment of Endocrine-Active Estrogenic Compounds

Safe, Stephen H., Pallaroni, Lea, Yoon, Kyungsil, Gaido, Kevin, Ross, Susan, McDonnell, Donald

Journal:

Environmental Health Perspectives

Year:

2002

Language:

english

File:

PDF, 155 KB

english, 2002

11

The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy

Suzanne E. Wardell, Jeffrey R. Marks, Donald P. McDonnell

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 968 KB

english, 2011

12

27-Hydroxycholesterol: a potential endogenous regulator of estrogen receptor signaling

Carolyn D. DuSell, Donald P. McDonnell

Journal:

Trends in Pharmacological Sciences

Year:

2008

Language:

english

File:

PDF, 198 KB

english, 2008

13

Estrogen Receptor (ER) Modulators Each Induce Distinct Conformational Changes in ER α and ER β

Lisa A. Paige, Dale J. Christensen, Hanne Grøn, John D. Norris, Elizabeth B. Gottlin, Karen M. Padilla, Ching-yi Chang, Lawrence M. Ballas, Paul T. Hamilton, Donald P. McDonnell and Dana M. Fowlkes

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.50 MB

english, 1999

14

Linking Ligand-Induced Alterations in Androgen Receptor Structure to Differential Gene Expression: A First Step in the Rational Design of Selective Androgen Receptor Modulators

Kazmin, Dmitri, Prytkova, Tatiana, Cook, C. Edgar, Wolfinger, Russell, Chu, Tzu-Ming, Beratan, David, Norris, J. D., Chang, Ching-yi, McDonnell, Donald P.

Journal:

Molecular Endocrinology

Year:

2006

Language:

english

File:

PDF, 934 KB

english, 2006

15

Activation of the Aryl-Hydrocarbon Receptor Inhibits Invasive and Metastatic Features of Human Breast Cancer Cells and Promotes Breast Cancer Cell Differentiation

Hall, Julie M., Barhoover, Melissa A., Kazmin, Dmitri, McDonnell, Donald P., Greenlee, William F., Thomas, Russell S.

Journal:

Molecular Endocrinology

Year:

2010

Language:

english

File:

PDF, 332 KB

english, 2010

16

Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader

Wardell, Suzanne E, Nelson, Erik R, Chao, Christina A, Alley, Holly M, McDonnell, Donald P

Journal:

Endocrine Related Cancer

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

17

Minireview: Nuclear Receptors, Hematopoiesis, and Stem Cells

Chute, John P., Ross, Joel R., McDonnell, Donald P.

Journal:

Molecular Endocrinology

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

18

Ozone-induced Inflammation in the Lower Airways of Human Subjects

Koren, Hillel S., Devlin, Robert B., Graham, Delores E., Mann, Richard, McGee, Maria P., Horstman, Donald H., Kozumbo, Walter J., Becker, Susanne, House, Dennis E., McDonnell, William F., Bromberg, Ph

Journal:

American Review of Respiratory Disease

Year:

1989

Language:

english

File:

PDF, 1.01 MB

english, 1989

19

The molecular pharmacology of estrogen receptor modulators: Implications for the treatment of breast cancer.

McDonnell, Donald P

Journal:

Clinical Cancer Research

Year:

2005

Language:

english

File:

PDF, 239 KB

english, 2005

20

Kinetic characterization of the interaction of biotinylated human interleukin 5 with an Fc chimera of its receptor α subunit and development of an ELISA screening assay using real-time interaction biosensor analysis

Donald Bennett, Thomas Morton, Ann Breen, Robert Hertzberg, Donna Cusimano, Edward Appelbaum, Peter McDonnell, Peter Young, Rosalie Matico, Irwin Chaiken

Journal:

Journal of Molecular Recognition

Year:

1995

Language:

english

File:

PDF, 736 KB

english, 1995

21

Definition of the Molecular Basis for Estrogen Receptor-Related Receptor-α-Cofactor Interactions

Gaillard, Stéphanie, Dwyer, Mary A., McDonnell, Donald P.

Journal:

Molecular Endocrinology

Year:

2007

Language:

english

File:

PDF, 681 KB

english, 2007

22

Induction of Krüppel-Like Factor 5 Expression by Androgens Results in Increased CXCR4-Dependent Migration of Prostate Cancer Cells in Vitro

Frigo, Daniel E., Sherk, Andrea B., Wittmann, Bryan M., Norris, John D., Wang, Qianben, Joseph, James D., Toner, Aidan P., Brown, Myles, McDonnell, Donald P.

Journal:

Molecular Endocrinology

Year:

2009

Language:

english

File:

PDF, 366 KB

english, 2009

23

Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors

Anderson, Grace R., Wardell, Suzanne E., Cakir, Merve, Yip, Catherine, Ahn, Yeong-ran, Ali, Moiez, Yllanes, Alexander P., Chao, Christina A., McDonnell, Donald P., Wood, Kris C.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.80 MB

english, 2018

24

Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRγ

Esther Y.H. Chao, Jon L. Collins, Stéphanie Gaillard, Aaron B. Miller, Liping Wang, Lisa A. Orband-Miller, Robert T. Nolte, Donald P. McDonnell, Timothy M. Willson, William J. Zuercher

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 171 KB

english, 2006

25

Inhibition of Aldehyde Dehydrogenase Expands Hematopoietic Stem Cells with Radioprotective Capacity

Garrett G. Muramoto, J. Lauren Russell, Rachid Safi, Alice B. Salter, Heather A. Himburg, Pamela Daher, Sarah K. Meadows, Phuong Doan, Robert W. Storms, Nelson J. Chao, Donald P. McDonnell, John P. Ch

Journal:

Year:

2010

Language:

english

File:

PDF, 867 KB

english, 2010

26

Bisphenol A interacts with the estrogen receptor α in a distinct manner from estradiol

Janet C. Gould, Linda S. Leonard, Susan C. Maness, Brandee L. Wagner, Kevin Conner, Tim Zacharewski, Steve Safe, Donald P. McDonnell, Kevin W. Gaido

Journal:

Molecular and Cellular Endocrinology

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998

27

On the Intractability of Estrogen-Related Receptor α as a Target for Activation by Small Molecules

Hyatt, Stephen M., Lockamy, Elizabeth L., Stein, Rebecca A., McDonnell, Donald P., Miller, Aaron B., Orband-Miller, Lisa A., Willson, Timothy M., Zuercher, William J.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

28

Direct Interactions between Corepressors and Coactivators Permit the Integration of Nuclear Receptor-Mediated Repression and Activation

Li, Xiaolin, Kimbrel, Erin A., Kenan, Daniel J., McDonnell, Donald P.

Journal:

Molecular Endocrinology

Year:

2002

Language:

english

File:

PDF, 344 KB

english, 2002

29

Identification of a Third Autonomous Activation Domain within the Human Estrogen Receptor

Norris, John D., Fan, Daju, Kerner, Sandra A., McDonnell, Donald P.

Journal:

Molecular Endocrinology

Year:

1997

Language:

english

File:

PDF, 3.23 MB

english, 1997

30

Structural Organization and Regulation of the Chicken Estrogen Receptor

Maxwell, Beth Lynn, McDonnell, Donald P., Conneely, Orla M., Schulz, Tanya Z., Greene, Geoffrey L., O'Malley, Bert W.

Journal:

Molecular Endocrinology

Year:

1987

Language:

english

File:

PDF, 1.81 MB

english, 1987

31

Targeting mutant estrogen receptors

Wardell, Suzanne E, Norris, John D, McDonnell, Donald P

Journal:

Year:

2019

Language:

english

File:

PDF, 407 KB

english, 2019

32

Mechanisms of Progesterone Receptor Inhibition of Inflammatory Responses in Cellular Models of Breast Cancer

Kobayashi, Sakiko, Stice, James P., Kazmin, Dmitri, Wittmann, Bryan M., Kimbrel, Erin A., Edwards, Dean P., Chang, Ching-Yi, McDonnell, Donald. P.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

File:

PDF, 58 KB

2010

33

Long-term Successful Weight Loss Improves Vascular Endothelial Function in Severely Obese Individuals

Sherman J. Bigornia, Melanie M. Mott, Donald T. Hess, Caroline M. Apovian, Marie E. McDonnell, Mai-Ann Duess, Matthew A. Kluge, Antonino J. Fiscale, Joseph A. Vita, Noyan Gokce

Journal:

Year:

2010

Language:

english

File:

PDF, 173 KB

english, 2010

34

The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer

Ching-yi Chang, Dmitri Kazmin, Jeff S. Jasper, Rebecca Kunder, William J. Zuercher, Donald P. McDonnell

Journal:

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

35

4,4′-Unsymmetrically substituted 3,3′-biphenyl alpha helical proteomimetics as potential coactivator binding inhibitors

Weiser, Patrick T., Chang, Ching-Yi, McDonnell, Donald P., Hanson, Robert N.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 816 KB

english, 2014

36

The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens 1

Hall, Julie M., McDonnell, Donald P.

Journal:

Year:

1999

Language:

english

File:

PDF, 1.63 MB

english, 1999

37

Lysine-Specific Histone Demethylase 1 Inhibitors Control Breast Cancer Proliferation in ERα-Dependent and -Independent Manners

Pollock, Julie A., Larrea, Michelle D., Jasper, Jeff S., McDonnell, Donald P., McCafferty, Dewey G.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 3.69 MB

english, 2012

38

Mining the Complexities of the Estrogen Signaling Pathways for Novel Therapeutics

McDonnell, Donald P.

Journal:

Year:

2003

Language:

english

File:

PDF, 60 KB

english, 2003

39

Comparative Analyses of Mechanistic Differences Among Antiestrogens 1

Wijayaratne, Ashini L., Nagel, Susan C., Paige, Lisa A., Christensen, Dale J., Norris, John D., Fowlkes, Dana M., McDonnell, Donald P.

Journal:

Year:

1999

Language:

english

File:

PDF, 1.13 MB

english, 1999

40

The Nuclear Receptor-Coactivator Interaction Surface as a Target for Peptide Antagonists of the Peroxisome Proliferator-Activated Receptors

Mettu, Niharika B., Stanley, Thomas B., Dwyer, Mary A., Jansen, Michelle S., Allen, John E., Hall, Julie M., McDonnell, Donald P.

Journal:

Molecular Endocrinology

Year:

2007

Language:

english

File:

PDF, 678 KB

english, 2007

41

Validation of histone deacetylase 3 as a therapeutic target in castration-resistant prostate cancer

McLeod, Abigail B., Stice, James P., Wardell, Suzanne E., Alley, Holly M., Chang, Ching-yi, McDonnell, Donald P.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.27 MB

english, 2017

42

The vitamin D receptor interacts preferentially with DRIP205-like LxxLL motifs

Lee A. Zella, Ching-Yi Chang, Donald P. McDonnell, J. Wesley Pike

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 281 KB

english, 2007

43

Molteno Implant for Control of Glaucoma in Eyes after Penetrating Keratoplasty

McDonnell, Peter J., Robin, Jeffrey B., Schanzlin, David J., Minckler, Donald, Baerveldt, George, Smith, Ronald E., Heuer, Dale

Journal:

Year:

1988

Language:

english

File:

PDF, 1.02 MB

english, 1988

44

27-hydroxycholesterol, an endogenous SERM, and risk of fracture in postmenopausal women: A nested case-cohort study in the Women's Health Initiative

Chang, Po-Yin, Feldman, David, Stefanick, Marcia L., McDonnell, Donald P., Thompson, Bonne M., McDonald, Jeffrey G., Lee, Jennifer S.

Journal:

Journal of Bone and Mineral Research

Year:

2018

File:

PDF, 772 KB

2018

45

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance

Salami, Jemilat, Alabi, Shanique, Willard, Ryan R., Vitale, Nick J., Wang, Jing, Dong, Hanqing, Jin, Meizhong, McDonnell, Donald P., Crew, Andrew P., Neklesa, Taavi K., Crews, Craig M.

Journal:

Communications Biology

Year:

2018

Language:

english

File:

PDF, 1.37 MB

english, 2018

46

Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer

Park, Sunghee, Safi, Rachid, Liu, Xiaojing, Baldi, Robert, Liu, Wen, Liu, Juan, Locasale, Jason W., Chang, Ching-yi, McDonnell, Donald P.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.26 MB

english, 2019

47

Nuclear Hormone Receptors as Targets for New Drug Discovery

McDonnell, Donald P., Vegeto, Elisabetta, Gleeson, Martin A. G.

Journal:

Nature Biotechnology

Year:

1993

File:

PDF, 822 KB

1993

48

Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP

Ortlund, Eric A, Lee, Yoonkwang, Solomon, Isaac H, Hager, Janet M, Safi, Rachid, Choi, Yunhee, Guan, Ziqiang, Tripathy, Ashutosh, Raetz, Christian R H, McDonnell, Donald P

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 889 KB

english, 2005

49

The Homeodomain Protein HOXB13 Regulates the Cellular Response to Androgens

John D. Norris, Ching-Yi Chang, Bryan M. Wittmann, Rebecca S. Kunder, Huaxia Cui, Daju Fan, James D. Joseph, Donald P. McDonnell

Journal:

Year:

2009

Language:

english

File:

PDF, 1.99 MB

english, 2009

50

The human progesterone receptor A-form functions as a transcriptional modulator of mineralocorticoid receptor transcriptional acitivity

McDonnell, Donald P., Shahbaz, Mauoucher M., Vegeto, Elisabetta, Goldman, Mark E.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1994

Language:

english

File:

PDF, 686 KB

english, 1994

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